Clinical Trials Update

In the past year, Roche initiated a new multi-national screening protocol to assess individuals with Down syndrome, aged 12-30. This is a screening protocol to assess adults and adolescents with Down syndrome for eligibility in an upcoming study of RG1662. Participants will undergo assessments to evaluate their eligibility for potential enrollment in an anticipated Phase II clinical study which will evaluate the efficacy, safety and tolerability of RG1662. This molecule has been demonstrated in mouse models to restore more balanced neurotransmission and improve learning. 

Balance Therapeutics is continuing its Phase 1b clinical trial at sites in Australia. The compound being studied in the trial, BTD-001 is well understood and has been in use for a variety of conditions for decade. The study is looking at the potential for BTD-001 treatment to improve memory, language, and learning.

Elan Corporation has a trial underway testing a compound that may reduce beta-amyloid aggregation. This aggregation is a contributor to plaque formation observed in persons with Alzheimer's disease. 

Our brief and informative infographic provides more detail on some of the pathways that contribute to cognitive impairment in Down syndrome. This useful primer on Down syndrome cognitive research is also available in print format. Contact info@researchds.org if you would like copies for sharing.

RDS 24-Hour Relay Run for Research

 

The RDS Inaugural 24-Hour Relay Run for Research is designed as a team event, in which each team member takes a turn running 1 mile around a 1-mile loop. Upon completing the mile, that team member will pass a baton to the next runner up. The run will continue as such for a 24-hour period beginning at 4:00 p.m. on Friday and ending at 4:00 p.m. on Saturday. 

Runners raise money by asking for sponsorships/donations per mile. Individual sponsors may donate 10¢, 15¢, or 25¢ or more per mile for every mile the team completes in the 24-hour period. It is perfectly fine to make a flat donation as well…any donation is greatly appreciated! 

The relay run registration form can be found here. 

The sponsor/donate form can be found here.